Sevoflurane exposure may cause dysplasia of dendritic spines and result in fine motor dysfunction in developing mouse through the PI3K/AKT/mTOR pathway

Sevoflurane has become one of the most widely used volatile anesthetics in pediatric surgery. However, sevoflurane exposure may interfere with dendritic development and synaptogenesis, resulting in brain function impairment. The PI3K/AKT/mTOR pathway plays an important role in dendritic development...

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Detalles Bibliográficos
Autores principales: Zhong, Linhong, Ma, Xiaofan, Niu, Yixuan, Zhang, Lei, Xue, Zhenyu, Yan, Jia, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554089/
https://www.ncbi.nlm.nih.gov/pubmed/36248658
http://dx.doi.org/10.3389/fnins.2022.1006175

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