Circulating HMGB1 is increased in myelodysplastic syndrome but not in other bone marrow failure syndromes: proof-of-concept cross-sectional study

BACKGROUND: Myelodysplastic syndrome (MDS) is associated with persistent immune activation. High mobility group box-1 (HMGB1) is a ubiquitous, functionally diverse, non-histone intranuclear protein. During acute and chronic inflammatory states, HMGB1 is actively released by inflammatory cells, furth...

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Detalles Bibliográficos
Autores principales: Apodaca-Chávez, Elia, Demichelis-Gómez, Roberta, Rosas-López, Adriana, Mejía-Domínguez, Nancy R., Galvan-López, Isabela, Addorosio, Meghan, Tracey, Kevin J., Valdés-Ferrer, Sergio Iván
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554121/
https://www.ncbi.nlm.nih.gov/pubmed/36246421
http://dx.doi.org/10.1177/20406207221125990

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