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Myeloid hypoxia-inducible factor HIF1A provides cardio-protection during ischemia and reperfusion via induction of netrin-1

The transcription factor hypoxia-inducible factor HIF1A induces cardioprotection from ischemia and reperfusion injury. Here, we investigate tissue-specific pathways that are critical for HIF1A-elicited tissue protection. Initial studies showed that mice with induced global Hif1a deletion (Hif1a(loxP...

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Detalles Bibliográficos
Autores principales:	Heck-Swain, Ka Lin, Li, Jiwen, Ruan, Wei, Yuan, Xiaoyi, Wang, Yanyu, Koeppen, Michael, Eltzschig, Holger K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554136/ https://www.ncbi.nlm.nih.gov/pubmed/36247475 http://dx.doi.org/10.3389/fcvm.2022.970415

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