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The Therapeutic Effects of a PEDF-Derived Short Peptide on Murine Experimental Dry Eye Involves Suppression of MMP-9 and Inflammation

PURPOSE: To evaluate the efficacy of a pigment epithelium-derived factor (PEDF)-derived short peptide 29-mer, on the treatment and prevention of experimental dry eye (EDE). METHODS: C57BL/6 mice were housed in a low humidity controlled environment chamber for 14 days to induce EDE. The 29-mer was ad...

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Detalles Bibliográficos
Autores principales: Ho, Tsung-Chuan, Fan, Nai-Wen, Yeh, Shu-I, Chen, Show-Li, Tsao, Yeou-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554226/
https://www.ncbi.nlm.nih.gov/pubmed/36201200
http://dx.doi.org/10.1167/tvst.11.10.12

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