SMOC2 gene interacts with APOL1 in the development of end-stage kidney disease: A genome-wide association study

BACKGROUND: Some but not all African-Americans (AA) who carry APOL1 nephropathy risk variants (APOL1) develop kidney failure (end-stage kidney disease, ESKD). To identify genetic modifiers, we assessed gene–gene interactions in a large prospective cohort of the REasons for Geographic and Racial Diff...

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Detalles Bibliográficos
Autores principales: Chaudhary, Ninad S., Armstrong, Nicole D., Hidalgo, Bertha A., Gutiérrez, Orlando M., Hellwege, Jacklyn N., Limdi, Nita A., Reynolds, Richard J., Judd, Suzanne E., Nadkarni, Girish N., Lange, Leslie, Winkler, Cheryl A., Kopp, Jeffrey B., Arnett, Donna K., Tiwari, Hemant K., Irvin, Marguerite R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554233/
https://www.ncbi.nlm.nih.gov/pubmed/36250097
http://dx.doi.org/10.3389/fmed.2022.971297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554233/
https://www.ncbi.nlm.nih.gov/pubmed/36250097
http://dx.doi.org/10.3389/fmed.2022.971297

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