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HRD-MILN: Accurately estimate tumor homologous recombination deficiency status from targeted panel sequencing data

Homologous recombination deficiency (HRD) is a critical feature guiding drug and treatment selection, mainly for ovarian and breast cancers. As it cannot be directly observed, HRD status is estimated on a small set of genomic instability features from sequencing data. The existing methods often perf...

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Detalles Bibliográficos
Autores principales:	Wang, Xuwen, Xu, Ying, Zhang, Yinbin, Wang, Shenjie, Zhang, Xuanping, Yi, Xin, Zhang, Shuqun, Wang, Jiayin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554509/ https://www.ncbi.nlm.nih.gov/pubmed/36246633 http://dx.doi.org/10.3389/fgene.2022.990244

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