Malnutrition leads to increased inflammation and expression of tuberculosis risk signatures in recently exposed household contacts of pulmonary tuberculosis

BACKGROUND: Most individuals exposed to Mycobacterium tuberculosis (Mtb) develop latent tuberculosis infection (LTBI) and remain at risk for progressing to active tuberculosis disease (TB). Malnutrition is an important risk factor driving progression from LTBI to TB. However, the performance of bloo...

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Detalles Bibliográficos
Autores principales: VanValkenburg, Arthur, Kaipilyawar, Vaishnavi, Sarkar, Sonali, Lakshminarayanan, Subitha, Cintron, Chelsie, Prakash Babu, Senbagavalli, Knudsen, Selby, Joseph, Noyal Mariya, Horsburgh, C. Robert, Sinha, Pranay, Ellner, Jerrold J., Narasimhan, Prakash Babu, Johnson, W. Evan, Hochberg, Natasha S., Salgame, Padmini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554585/
https://www.ncbi.nlm.nih.gov/pubmed/36248906
http://dx.doi.org/10.3389/fimmu.2022.1011166

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