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Cross-reactivity between vaccine antigens from the chitin deacetylase protein family improves survival in a mouse model of cryptococcosis
Meningitis due to the fungal pathogen Cryptococcus neoformans is estimated to cause nearly 200,000 deaths annually, mostly in resource-limited regions. We previously identified cryptococcal protein antigens which, when delivered in glucan particles, afford vaccine-mediated protection against an othe...
Autores principales: | Hester, Maureen M., Oliveira, Lorena V. N., Wang, Ruiying, Mou, Zhongming, Lourenco, Diana, Ostroff, Gary R., Specht, Charles A., Levitz, Stuart M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554598/ https://www.ncbi.nlm.nih.gov/pubmed/36248898 http://dx.doi.org/10.3389/fimmu.2022.1015586 |
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