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Energy-Stress-Mediated AMPK Activation Promotes GPX4-Dependent Ferroptosis through the JAK2/STAT3/P53 Axis in Renal Cancer
Energy stress is an unfavorable condition that tumor cells are often exposed to. Ferroptosis is considered an emerging target for tumor therapy. However, the role of ferroptosis in energy stress in renal cancer is currently unknown. In this study, we found that glucose deprivation significantly enha...
Autores principales: | Li, Yanze, Zhang, Ye, Qiu, Qiangmin, Wang, Lei, Mao, Hu, Hu, Juncheng, Chen, Zhiyuan, Du, Yang, Liu, Xiuheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554664/ https://www.ncbi.nlm.nih.gov/pubmed/36246395 http://dx.doi.org/10.1155/2022/2353115 |
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