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Antimicrobial activities and mechanisms of extract and components of herbs in East Asia

Antibacterial drugs face increasing challenges due to drug resistance and adverse reactions, which has created a pressing need for the discovery and development of novel antibacterial drugs. Herbs have played an important role in the treatment of infectious diseases. This review aims to summarize, a...

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Detalles Bibliográficos
Autores principales: Liang, Jingru, Huang, Xuan, Ma, Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554739/
https://www.ncbi.nlm.nih.gov/pubmed/36320733
http://dx.doi.org/10.1039/d2ra02389j
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author Liang, Jingru
Huang, Xuan
Ma, Guo
author_facet Liang, Jingru
Huang, Xuan
Ma, Guo
author_sort Liang, Jingru
collection PubMed
description Antibacterial drugs face increasing challenges due to drug resistance and adverse reactions, which has created a pressing need for the discovery and development of novel antibacterial drugs. Herbs have played an important role in the treatment of infectious diseases. This review aims to summarize, analyze and evaluate the antibacterial activities and mechanisms of components from popular herbs in East Asia. In this review, we have searched and summarized the scientific papers published during the past twenty-year period from electronic databases such as PubMed, ScienceDirect, and Web of Science. These herbs and their components, including alkaloids, flavonoids, essential oils, terpenes, organic acids, coumarins and lignans, display potential antimicrobial effects. Herbal medicine formulas (HMFs) usually show stronger antibacterial activity than single herbs. Herbs and HMFs bring forth antibacterial activities by damaging cell membranes and walls, inhibiting nucleic acid and protein synthesis, and increasing intracellular osmotic pressure. These herbs and their components can be developed as potential and promising novel antibacterial herbal products.
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spelling pubmed-95547392022-10-31 Antimicrobial activities and mechanisms of extract and components of herbs in East Asia Liang, Jingru Huang, Xuan Ma, Guo RSC Adv Chemistry Antibacterial drugs face increasing challenges due to drug resistance and adverse reactions, which has created a pressing need for the discovery and development of novel antibacterial drugs. Herbs have played an important role in the treatment of infectious diseases. This review aims to summarize, analyze and evaluate the antibacterial activities and mechanisms of components from popular herbs in East Asia. In this review, we have searched and summarized the scientific papers published during the past twenty-year period from electronic databases such as PubMed, ScienceDirect, and Web of Science. These herbs and their components, including alkaloids, flavonoids, essential oils, terpenes, organic acids, coumarins and lignans, display potential antimicrobial effects. Herbal medicine formulas (HMFs) usually show stronger antibacterial activity than single herbs. Herbs and HMFs bring forth antibacterial activities by damaging cell membranes and walls, inhibiting nucleic acid and protein synthesis, and increasing intracellular osmotic pressure. These herbs and their components can be developed as potential and promising novel antibacterial herbal products. The Royal Society of Chemistry 2022-10-12 /pmc/articles/PMC9554739/ /pubmed/36320733 http://dx.doi.org/10.1039/d2ra02389j Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Liang, Jingru
Huang, Xuan
Ma, Guo
Antimicrobial activities and mechanisms of extract and components of herbs in East Asia
title Antimicrobial activities and mechanisms of extract and components of herbs in East Asia
title_full Antimicrobial activities and mechanisms of extract and components of herbs in East Asia
title_fullStr Antimicrobial activities and mechanisms of extract and components of herbs in East Asia
title_full_unstemmed Antimicrobial activities and mechanisms of extract and components of herbs in East Asia
title_short Antimicrobial activities and mechanisms of extract and components of herbs in East Asia
title_sort antimicrobial activities and mechanisms of extract and components of herbs in east asia
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554739/
https://www.ncbi.nlm.nih.gov/pubmed/36320733
http://dx.doi.org/10.1039/d2ra02389j
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