Cathepsin B deteriorates diabetic cardiomyopathy induced by streptozotocin via promoting NLRP3-mediated pyroptosis

Cathepsin B (CTSB), a member of lysosomal cathepsin, is involved in cell autophagy and apoptosis. We previously reported that CTSB increased cardiomyocyte apoptosis in mice heart during pressure overload, while the role of CTSB on diabetic cardiomyopathy has not been fully elucidated. The aim of thi...

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Detalles Bibliográficos
Autores principales: Liu, Chen, Yao, Qi, Hu, Tongtong, Cai, Zhulan, Xie, Qingwen, Zhao, Jinhua, Yuan, Yuan, Ni, Jian, Wu, Qing Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554743/
https://www.ncbi.nlm.nih.gov/pubmed/36250207
http://dx.doi.org/10.1016/j.omtn.2022.09.019

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