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Tuning the Loading and Release Properties of MicroRNA-Silencing Porous Silicon Nanoparticles by Using Chemically Diverse Peptide Nucleic Acid Payloads
[Image: see text] Peptide nucleic acids (PNAs) are a class of artificial oligonucleotide mimics that have garnered much attention as precision biotherapeutics for their efficient hybridization properties and their exceptional biological and chemical stability. However, the poor cellular uptake of PN...
Autores principales: | Neri, Martina, Kang, Jinyoung, Zuidema, Jonathan M., Gasparello, Jessica, Finotti, Alessia, Gambari, Roberto, Sailor, Michael J., Bertucci, Alessandro, Corradini, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554869/ https://www.ncbi.nlm.nih.gov/pubmed/34468123 http://dx.doi.org/10.1021/acsbiomaterials.1c00431 |
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