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Robust synthesis of 2′-azido modified RNA from 2′-amino precursors by diazotransfer reaction
Azides are versatile bioorthogonal reporter moieties that are commonly used for site-specific labeling and functionalization of RNA to probe its biology. The preparation of azido modified nucleic acids by solid-phase synthesis is problematic due to the inherent reactivity of P(iii) species with azid...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554934/ https://www.ncbi.nlm.nih.gov/pubmed/36172831 http://dx.doi.org/10.1039/d2ob01560a |