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Neuregulin-4 attenuates diabetic cardiomyopathy by regulating autophagy via the AMPK/mTOR signalling pathway
BACKGROUND: Diabetic cardiomyopathy is characterized by left ventricle dysfunction, cardiomyocyte apoptosis, and interstitial fibrosis and is a serious complication of diabetes mellitus (DM). Autophagy is a mechanism that is essential for maintaining normal heart morphology and function, and its dys...
Autores principales: | Wang, Hongchao, Wang, Lijie, Hu, Fuli, Wang, Pengfei, Xie, Yanan, Li, Fang, Guo, Bingyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9554973/ https://www.ncbi.nlm.nih.gov/pubmed/36221104 http://dx.doi.org/10.1186/s12933-022-01643-0 |
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