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Single Nucleus RNA-sequencing Reveals Altered Intercellular Communication and Dendritic Cell Activation in Nonobstructive Hypertrophic Cardiomyopathy

End stage, nonobstructive hypertrophic cardiomyopathy (HCM) is an intractable condition with no disease-specific therapies. To gain insights into the pathogenesis of nonobstructive HCM, we performed single nucleus RNA-sequencing (snRNA-seq) on human HCM hearts explanted at the time of cardiac transp...

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Detalles Bibliográficos
Autores principales: Codden, Christina J, Larson, Amy, Awata, Junya, Perera, Gayani, Chin, Michael T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555339/
https://www.ncbi.nlm.nih.gov/pubmed/36237479
http://dx.doi.org/10.26502/fccm.92920277