Ether lipid deficiency disrupts lipid homeostasis leading to ferroptosis sensitivity

Ferroptosis is an iron-dependent form of regulated cell death associated with uncontrolled membrane lipid peroxidation and destruction. Previously, we showed that dietary dihomo-gamma-linolenic acid (DGLA; 20: 3(n-6)) triggers ferroptosis in the germ cells of the model organism, Caenorhabditis elega...

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Detalles Bibliográficos
Autores principales: Perez, Marcos A., Clostio, Andrea J., Houston, Isabel R., Ruiz, Jimena, Magtanong, Leslie, Dixon, Scott J., Watts, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555615/
https://www.ncbi.nlm.nih.gov/pubmed/36178986
http://dx.doi.org/10.1371/journal.pgen.1010436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555615/
https://www.ncbi.nlm.nih.gov/pubmed/36178986
http://dx.doi.org/10.1371/journal.pgen.1010436

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