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Ether lipid deficiency disrupts lipid homeostasis leading to ferroptosis sensitivity
Ferroptosis is an iron-dependent form of regulated cell death associated with uncontrolled membrane lipid peroxidation and destruction. Previously, we showed that dietary dihomo-gamma-linolenic acid (DGLA; 20: 3(n-6)) triggers ferroptosis in the germ cells of the model organism, Caenorhabditis elega...
Autores principales: | Perez, Marcos A., Clostio, Andrea J., Houston, Isabel R., Ruiz, Jimena, Magtanong, Leslie, Dixon, Scott J., Watts, Jennifer L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555615/ https://www.ncbi.nlm.nih.gov/pubmed/36178986 http://dx.doi.org/10.1371/journal.pgen.1010436 |
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