Upper cortical layer–driven network impairment in schizophrenia

Schizophrenia is one of the most widespread and complex mental disorders. To characterize the impact of schizophrenia, we performed single-nucleus RNA sequencing (snRNA-seq) of >220,000 neurons from the dorsolateral prefrontal cortex of patients with schizophrenia and matched controls. In additio...

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Detalles Bibliográficos
Autores principales: Batiuk, Mykhailo Y., Tyler, Teadora, Dragicevic, Katarina, Mei, Shenglin, Rydbirk, Rasmus, Petukhov, Viktor, Deviatiiarov, Ruslan, Sedmak, Dora, Frank, Erzsebet, Feher, Virginia, Habek, Nikola, Hu, Qiwen, Igolkina, Anna, Roszik, Lilla, Pfisterer, Ulrich, Garcia-Gonzalez, Diego, Petanjek, Zdravko, Adorjan, Istvan, Kharchenko, Peter V., Khodosevich, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555788/
https://www.ncbi.nlm.nih.gov/pubmed/36223459
http://dx.doi.org/10.1126/sciadv.abn8367

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