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Single-cell sequencing reveals effects of chemotherapy on the immune landscape and TCR/BCR clonal expansion in a relapsed ovarian cancer patient

Cancer recurrence and chemoresistance are the leading causes of death in high-grade serous ovarian cancer (HGSOC) patients. However, the unique role of the immune environment in tumor progression for relapsed chemo-resistant patients remains elusive. In single-cell resolution, we characterized a com...

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Detalles Bibliográficos
Autores principales:	Ren, Yanyu, Li, Runrong, Feng, Hanxiao, Xie, Jieying, Gao, Lin, Chu, Shuai, Li, Yan, Meng, Fanliang, Ning, Yunshan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9555851/ https://www.ncbi.nlm.nih.gov/pubmed/36248860 http://dx.doi.org/10.3389/fimmu.2022.985187

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