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The Expression of hnRNP A2/B1 in Benign and Malignant Lung Lesions and Its Early Diagnosis Value in NSCLC

Lung cancer in its occurrence and development of different stages exist different biological behavior changes. This paper studies the expression of heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 in benign and malignant lung lesions and its early diagnosis value of nonsmall-cell lung cancer (N...

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Autores principales: Gu, Wenchao, Gao, Xiwen, Wang, Linxun, Deng, Guoping, Huang, Jiaru, Yang, Junxia, Liu, Yuan, Liu, Qun, Sang, Hongyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556203/
https://www.ncbi.nlm.nih.gov/pubmed/36262980
http://dx.doi.org/10.1155/2022/5687245
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author Gu, Wenchao
Gao, Xiwen
Wang, Linxun
Deng, Guoping
Huang, Jiaru
Yang, Junxia
Liu, Yuan
Liu, Qun
Sang, Hongyang
author_facet Gu, Wenchao
Gao, Xiwen
Wang, Linxun
Deng, Guoping
Huang, Jiaru
Yang, Junxia
Liu, Yuan
Liu, Qun
Sang, Hongyang
author_sort Gu, Wenchao
collection PubMed
description Lung cancer in its occurrence and development of different stages exist different biological behavior changes. This paper studies the expression of heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 in benign and malignant lung lesions and its early diagnosis value of nonsmall-cell lung cancer (NSCLC), aiming to provide reference for the early diagnosis and therapy of NSCLC. Some lung surgery specimens are selected from January 2021 to March 2022. All cases received no radiotherapy and chemotherapy before surgery, including 90 sufferers with benign lung lesions as the contrast set. hnRNP A2/B1 expressions are measured for comparison. The experimental results show that for lung cancer sufferers, the positive expression of hnRNP A2/B1 in their malignant lesion tissue is notoriously higher than that in their benign lesion tissue, and hnRNP A2/B1 is differently expressed in different differentiation and in different stages.
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spelling pubmed-95562032022-10-18 The Expression of hnRNP A2/B1 in Benign and Malignant Lung Lesions and Its Early Diagnosis Value in NSCLC Gu, Wenchao Gao, Xiwen Wang, Linxun Deng, Guoping Huang, Jiaru Yang, Junxia Liu, Yuan Liu, Qun Sang, Hongyang Contrast Media Mol Imaging Research Article Lung cancer in its occurrence and development of different stages exist different biological behavior changes. This paper studies the expression of heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 in benign and malignant lung lesions and its early diagnosis value of nonsmall-cell lung cancer (NSCLC), aiming to provide reference for the early diagnosis and therapy of NSCLC. Some lung surgery specimens are selected from January 2021 to March 2022. All cases received no radiotherapy and chemotherapy before surgery, including 90 sufferers with benign lung lesions as the contrast set. hnRNP A2/B1 expressions are measured for comparison. The experimental results show that for lung cancer sufferers, the positive expression of hnRNP A2/B1 in their malignant lesion tissue is notoriously higher than that in their benign lesion tissue, and hnRNP A2/B1 is differently expressed in different differentiation and in different stages. Hindawi 2022-10-05 /pmc/articles/PMC9556203/ /pubmed/36262980 http://dx.doi.org/10.1155/2022/5687245 Text en Copyright © 2022 Wenchao Gu et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Gu, Wenchao
Gao, Xiwen
Wang, Linxun
Deng, Guoping
Huang, Jiaru
Yang, Junxia
Liu, Yuan
Liu, Qun
Sang, Hongyang
The Expression of hnRNP A2/B1 in Benign and Malignant Lung Lesions and Its Early Diagnosis Value in NSCLC
title The Expression of hnRNP A2/B1 in Benign and Malignant Lung Lesions and Its Early Diagnosis Value in NSCLC
title_full The Expression of hnRNP A2/B1 in Benign and Malignant Lung Lesions and Its Early Diagnosis Value in NSCLC
title_fullStr The Expression of hnRNP A2/B1 in Benign and Malignant Lung Lesions and Its Early Diagnosis Value in NSCLC
title_full_unstemmed The Expression of hnRNP A2/B1 in Benign and Malignant Lung Lesions and Its Early Diagnosis Value in NSCLC
title_short The Expression of hnRNP A2/B1 in Benign and Malignant Lung Lesions and Its Early Diagnosis Value in NSCLC
title_sort expression of hnrnp a2/b1 in benign and malignant lung lesions and its early diagnosis value in nsclc
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556203/
https://www.ncbi.nlm.nih.gov/pubmed/36262980
http://dx.doi.org/10.1155/2022/5687245
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