Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia Incidentally Detected by Fluorodeoxyglucose-positron Emission Tomography/Computed Tomography at a Health Checkup

We herein report a case of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph-ALL) that was incidentally detected by fluorodeoxyglucose-positron emission tomography ((18)F-FDG PET)/computed tomography (CT) at a health checkup. At that time, the findings of a physical examination and b...

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Detalles Bibliográficos
Autores principales: Kunieda, Hisako, Denda, Ryunosuke, Yamazaki, Kohei, Hirao, Maki, Tsukada, Yuiko, Iwabuchi, Yu, Shiomi, Eisuke, Watanabe, Shigeru, Okamoto, Shinichiro, Kikuchi, Takahide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556232/
https://www.ncbi.nlm.nih.gov/pubmed/35228421
http://dx.doi.org/10.2169/internalmedicine.8900-21
Descripción
Sumario:We herein report a case of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph-ALL) that was incidentally detected by fluorodeoxyglucose-positron emission tomography ((18)F-FDG PET)/computed tomography (CT) at a health checkup. At that time, the findings of a physical examination and blood tests were all normal, except for the diffuse bone marrow uptake (maximum standardized uptake value: 6.3). One month later, when the blood counts remained in the normal ranges, a bone marrow examination confirmed the diagnosis of Ph-ALL. Although a diffuse bone marrow uptake of (18)F-FDG is observed in some benign conditions, physicians should also consider the possibility of hematological malignancies, including acute leukemia, even when that is the only abnormal finding.

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