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Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia Incidentally Detected by Fluorodeoxyglucose-positron Emission Tomography/Computed Tomography at a Health Checkup

We herein report a case of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph-ALL) that was incidentally detected by fluorodeoxyglucose-positron emission tomography ((18)F-FDG PET)/computed tomography (CT) at a health checkup. At that time, the findings of a physical examination and b...

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Autores principales: Kunieda, Hisako, Denda, Ryunosuke, Yamazaki, Kohei, Hirao, Maki, Tsukada, Yuiko, Iwabuchi, Yu, Shiomi, Eisuke, Watanabe, Shigeru, Okamoto, Shinichiro, Kikuchi, Takahide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556232/
https://www.ncbi.nlm.nih.gov/pubmed/35228421
http://dx.doi.org/10.2169/internalmedicine.8900-21
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author Kunieda, Hisako
Denda, Ryunosuke
Yamazaki, Kohei
Hirao, Maki
Tsukada, Yuiko
Iwabuchi, Yu
Shiomi, Eisuke
Watanabe, Shigeru
Okamoto, Shinichiro
Kikuchi, Takahide
author_facet Kunieda, Hisako
Denda, Ryunosuke
Yamazaki, Kohei
Hirao, Maki
Tsukada, Yuiko
Iwabuchi, Yu
Shiomi, Eisuke
Watanabe, Shigeru
Okamoto, Shinichiro
Kikuchi, Takahide
author_sort Kunieda, Hisako
collection PubMed
description We herein report a case of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph-ALL) that was incidentally detected by fluorodeoxyglucose-positron emission tomography ((18)F-FDG PET)/computed tomography (CT) at a health checkup. At that time, the findings of a physical examination and blood tests were all normal, except for the diffuse bone marrow uptake (maximum standardized uptake value: 6.3). One month later, when the blood counts remained in the normal ranges, a bone marrow examination confirmed the diagnosis of Ph-ALL. Although a diffuse bone marrow uptake of (18)F-FDG is observed in some benign conditions, physicians should also consider the possibility of hematological malignancies, including acute leukemia, even when that is the only abnormal finding.
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spelling pubmed-95562322022-10-27 Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia Incidentally Detected by Fluorodeoxyglucose-positron Emission Tomography/Computed Tomography at a Health Checkup Kunieda, Hisako Denda, Ryunosuke Yamazaki, Kohei Hirao, Maki Tsukada, Yuiko Iwabuchi, Yu Shiomi, Eisuke Watanabe, Shigeru Okamoto, Shinichiro Kikuchi, Takahide Intern Med Case Report We herein report a case of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph-ALL) that was incidentally detected by fluorodeoxyglucose-positron emission tomography ((18)F-FDG PET)/computed tomography (CT) at a health checkup. At that time, the findings of a physical examination and blood tests were all normal, except for the diffuse bone marrow uptake (maximum standardized uptake value: 6.3). One month later, when the blood counts remained in the normal ranges, a bone marrow examination confirmed the diagnosis of Ph-ALL. Although a diffuse bone marrow uptake of (18)F-FDG is observed in some benign conditions, physicians should also consider the possibility of hematological malignancies, including acute leukemia, even when that is the only abnormal finding. The Japanese Society of Internal Medicine 2022-02-26 2022-09-15 /pmc/articles/PMC9556232/ /pubmed/35228421 http://dx.doi.org/10.2169/internalmedicine.8900-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kunieda, Hisako
Denda, Ryunosuke
Yamazaki, Kohei
Hirao, Maki
Tsukada, Yuiko
Iwabuchi, Yu
Shiomi, Eisuke
Watanabe, Shigeru
Okamoto, Shinichiro
Kikuchi, Takahide
Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia Incidentally Detected by Fluorodeoxyglucose-positron Emission Tomography/Computed Tomography at a Health Checkup
title Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia Incidentally Detected by Fluorodeoxyglucose-positron Emission Tomography/Computed Tomography at a Health Checkup
title_full Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia Incidentally Detected by Fluorodeoxyglucose-positron Emission Tomography/Computed Tomography at a Health Checkup
title_fullStr Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia Incidentally Detected by Fluorodeoxyglucose-positron Emission Tomography/Computed Tomography at a Health Checkup
title_full_unstemmed Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia Incidentally Detected by Fluorodeoxyglucose-positron Emission Tomography/Computed Tomography at a Health Checkup
title_short Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia Incidentally Detected by Fluorodeoxyglucose-positron Emission Tomography/Computed Tomography at a Health Checkup
title_sort philadelphia chromosome-positive acute lymphoblastic leukemia incidentally detected by fluorodeoxyglucose-positron emission tomography/computed tomography at a health checkup
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556232/
https://www.ncbi.nlm.nih.gov/pubmed/35228421
http://dx.doi.org/10.2169/internalmedicine.8900-21
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