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Idiopathic Obliterative Bronchiolitis in a Young Woman: A Rare Case of a Transbronchial Lung Biopsy Contributing to the Diagnosis

Idiopathic obliterative bronchiolitis (OB) is a rare disease that usually requires a surgical lung biopsy. A 25-year-old woman with progressive exertional dyspnea for several months showed a severe mixed restrictive and obstructive pattern on spirometry. Chest computed tomography showed a mosaic pat...

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Autores principales: Yoshii, Naoko, Kamoi, Hiroshi, Matsui, Erika, Sato, Kanako, Nakai, Toshiyuki, Yamada, Kazuhiro, Watanabe, Tetsuya, Asai, Kazuhisa, Kanazawa, Hiroshi, Kawaguchi, Tomoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556245/
https://www.ncbi.nlm.nih.gov/pubmed/35249917
http://dx.doi.org/10.2169/internalmedicine.8490-21
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author Yoshii, Naoko
Kamoi, Hiroshi
Matsui, Erika
Sato, Kanako
Nakai, Toshiyuki
Yamada, Kazuhiro
Watanabe, Tetsuya
Asai, Kazuhisa
Kanazawa, Hiroshi
Kawaguchi, Tomoya
author_facet Yoshii, Naoko
Kamoi, Hiroshi
Matsui, Erika
Sato, Kanako
Nakai, Toshiyuki
Yamada, Kazuhiro
Watanabe, Tetsuya
Asai, Kazuhisa
Kanazawa, Hiroshi
Kawaguchi, Tomoya
author_sort Yoshii, Naoko
collection PubMed
description Idiopathic obliterative bronchiolitis (OB) is a rare disease that usually requires a surgical lung biopsy. A 25-year-old woman with progressive exertional dyspnea for several months showed a severe mixed restrictive and obstructive pattern on spirometry. Chest computed tomography showed a mosaic pattern, and pulmonary ventilation-perfusion scintigraphy showed a matched defect. The bronchoscopic specimens obtained from both the alveolar and bronchiolar regions of the predicted lesion area contributed to the diagnosis of OB. She had no underlying causes of secondary OB, and she was diagnosed with idiopathic OB. Since lung transplantation was indicated, she was referred to a lung transplantation-certified hospital.
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spelling pubmed-95562452022-10-27 Idiopathic Obliterative Bronchiolitis in a Young Woman: A Rare Case of a Transbronchial Lung Biopsy Contributing to the Diagnosis Yoshii, Naoko Kamoi, Hiroshi Matsui, Erika Sato, Kanako Nakai, Toshiyuki Yamada, Kazuhiro Watanabe, Tetsuya Asai, Kazuhisa Kanazawa, Hiroshi Kawaguchi, Tomoya Intern Med Case Report Idiopathic obliterative bronchiolitis (OB) is a rare disease that usually requires a surgical lung biopsy. A 25-year-old woman with progressive exertional dyspnea for several months showed a severe mixed restrictive and obstructive pattern on spirometry. Chest computed tomography showed a mosaic pattern, and pulmonary ventilation-perfusion scintigraphy showed a matched defect. The bronchoscopic specimens obtained from both the alveolar and bronchiolar regions of the predicted lesion area contributed to the diagnosis of OB. She had no underlying causes of secondary OB, and she was diagnosed with idiopathic OB. Since lung transplantation was indicated, she was referred to a lung transplantation-certified hospital. The Japanese Society of Internal Medicine 2022-03-05 2022-09-15 /pmc/articles/PMC9556245/ /pubmed/35249917 http://dx.doi.org/10.2169/internalmedicine.8490-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Yoshii, Naoko
Kamoi, Hiroshi
Matsui, Erika
Sato, Kanako
Nakai, Toshiyuki
Yamada, Kazuhiro
Watanabe, Tetsuya
Asai, Kazuhisa
Kanazawa, Hiroshi
Kawaguchi, Tomoya
Idiopathic Obliterative Bronchiolitis in a Young Woman: A Rare Case of a Transbronchial Lung Biopsy Contributing to the Diagnosis
title Idiopathic Obliterative Bronchiolitis in a Young Woman: A Rare Case of a Transbronchial Lung Biopsy Contributing to the Diagnosis
title_full Idiopathic Obliterative Bronchiolitis in a Young Woman: A Rare Case of a Transbronchial Lung Biopsy Contributing to the Diagnosis
title_fullStr Idiopathic Obliterative Bronchiolitis in a Young Woman: A Rare Case of a Transbronchial Lung Biopsy Contributing to the Diagnosis
title_full_unstemmed Idiopathic Obliterative Bronchiolitis in a Young Woman: A Rare Case of a Transbronchial Lung Biopsy Contributing to the Diagnosis
title_short Idiopathic Obliterative Bronchiolitis in a Young Woman: A Rare Case of a Transbronchial Lung Biopsy Contributing to the Diagnosis
title_sort idiopathic obliterative bronchiolitis in a young woman: a rare case of a transbronchial lung biopsy contributing to the diagnosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556245/
https://www.ncbi.nlm.nih.gov/pubmed/35249917
http://dx.doi.org/10.2169/internalmedicine.8490-21
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