Cargando…
Mutagenic, Carcinogenic, and Teratogenic Effect of Heavy Metals
Heavy metal (HM)-induced toxicity and its associated complications have become a major issue in the medical world. HMs are not biodegradable, enter into the food chain, and gets accumulated in the living systems. Increased concentrations and accumulation of HMs can cause severely damaging effects an...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556253/ https://www.ncbi.nlm.nih.gov/pubmed/36248437 http://dx.doi.org/10.1155/2022/8011953 |
_version_ | 1784807034740277248 |
---|---|
author | Dasharathy, Sukeerthi Arjunan, Selvam Maliyur Basavaraju, Anusha Murugasen, Vidya Ramachandran, Saravanan Keshav, Rohini Murugan, Rajadurai |
author_facet | Dasharathy, Sukeerthi Arjunan, Selvam Maliyur Basavaraju, Anusha Murugasen, Vidya Ramachandran, Saravanan Keshav, Rohini Murugan, Rajadurai |
author_sort | Dasharathy, Sukeerthi |
collection | PubMed |
description | Heavy metal (HM)-induced toxicity and its associated complications have become a major issue in the medical world. HMs are not biodegradable, enter into the food chain, and gets accumulated in the living systems. Increased concentrations and accumulation of HMs can cause severely damaging effects and severe complications in living organisms and can even lead to the death of the organism. In Ayurvedic medicine, ingredients of natural origin, including whole plants or certain portions of the plant, animal sources, and minerals, are used for therapeutic purposes as medicine, both alone and in combination. HM such as cadmium, copper, zinc, lead, chromium, nickel, and arsenic cause hazardous effects on animals, human health, and the environment. This review focuses on mutagenic, carcinogenic, and teratogenic effects of HM , mechanism, organ toxicity, available remedies in the market, and their side effects. Also, emphasis is given to alternative systems of medicine to treat HM toxicity. |
format | Online Article Text |
id | pubmed-9556253 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-95562532022-10-13 Mutagenic, Carcinogenic, and Teratogenic Effect of Heavy Metals Dasharathy, Sukeerthi Arjunan, Selvam Maliyur Basavaraju, Anusha Murugasen, Vidya Ramachandran, Saravanan Keshav, Rohini Murugan, Rajadurai Evid Based Complement Alternat Med Review Article Heavy metal (HM)-induced toxicity and its associated complications have become a major issue in the medical world. HMs are not biodegradable, enter into the food chain, and gets accumulated in the living systems. Increased concentrations and accumulation of HMs can cause severely damaging effects and severe complications in living organisms and can even lead to the death of the organism. In Ayurvedic medicine, ingredients of natural origin, including whole plants or certain portions of the plant, animal sources, and minerals, are used for therapeutic purposes as medicine, both alone and in combination. HM such as cadmium, copper, zinc, lead, chromium, nickel, and arsenic cause hazardous effects on animals, human health, and the environment. This review focuses on mutagenic, carcinogenic, and teratogenic effects of HM , mechanism, organ toxicity, available remedies in the market, and their side effects. Also, emphasis is given to alternative systems of medicine to treat HM toxicity. Hindawi 2022-10-05 /pmc/articles/PMC9556253/ /pubmed/36248437 http://dx.doi.org/10.1155/2022/8011953 Text en Copyright © 2022 Sukeerthi Dasharathy et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Dasharathy, Sukeerthi Arjunan, Selvam Maliyur Basavaraju, Anusha Murugasen, Vidya Ramachandran, Saravanan Keshav, Rohini Murugan, Rajadurai Mutagenic, Carcinogenic, and Teratogenic Effect of Heavy Metals |
title | Mutagenic, Carcinogenic, and Teratogenic Effect of Heavy Metals |
title_full | Mutagenic, Carcinogenic, and Teratogenic Effect of Heavy Metals |
title_fullStr | Mutagenic, Carcinogenic, and Teratogenic Effect of Heavy Metals |
title_full_unstemmed | Mutagenic, Carcinogenic, and Teratogenic Effect of Heavy Metals |
title_short | Mutagenic, Carcinogenic, and Teratogenic Effect of Heavy Metals |
title_sort | mutagenic, carcinogenic, and teratogenic effect of heavy metals |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556253/ https://www.ncbi.nlm.nih.gov/pubmed/36248437 http://dx.doi.org/10.1155/2022/8011953 |
work_keys_str_mv | AT dasharathysukeerthi mutageniccarcinogenicandteratogeniceffectofheavymetals AT arjunanselvam mutageniccarcinogenicandteratogeniceffectofheavymetals AT maliyurbasavarajuanusha mutageniccarcinogenicandteratogeniceffectofheavymetals AT murugasenvidya mutageniccarcinogenicandteratogeniceffectofheavymetals AT ramachandransaravanan mutageniccarcinogenicandteratogeniceffectofheavymetals AT keshavrohini mutageniccarcinogenicandteratogeniceffectofheavymetals AT muruganrajadurai mutageniccarcinogenicandteratogeniceffectofheavymetals |