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Mutagenic, Carcinogenic, and Teratogenic Effect of Heavy Metals

Heavy metal (HM)-induced toxicity and its associated complications have become a major issue in the medical world. HMs are not biodegradable, enter into the food chain, and gets accumulated in the living systems. Increased concentrations and accumulation of HMs can cause severely damaging effects an...

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Autores principales: Dasharathy, Sukeerthi, Arjunan, Selvam, Maliyur Basavaraju, Anusha, Murugasen, Vidya, Ramachandran, Saravanan, Keshav, Rohini, Murugan, Rajadurai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556253/
https://www.ncbi.nlm.nih.gov/pubmed/36248437
http://dx.doi.org/10.1155/2022/8011953
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author Dasharathy, Sukeerthi
Arjunan, Selvam
Maliyur Basavaraju, Anusha
Murugasen, Vidya
Ramachandran, Saravanan
Keshav, Rohini
Murugan, Rajadurai
author_facet Dasharathy, Sukeerthi
Arjunan, Selvam
Maliyur Basavaraju, Anusha
Murugasen, Vidya
Ramachandran, Saravanan
Keshav, Rohini
Murugan, Rajadurai
author_sort Dasharathy, Sukeerthi
collection PubMed
description Heavy metal (HM)-induced toxicity and its associated complications have become a major issue in the medical world. HMs are not biodegradable, enter into the food chain, and gets accumulated in the living systems. Increased concentrations and accumulation of HMs can cause severely damaging effects and severe complications in living organisms and can even lead to the death of the organism. In Ayurvedic medicine, ingredients of natural origin, including whole plants or certain portions of the plant, animal sources, and minerals, are used for therapeutic purposes as medicine, both alone and in combination. HM such as cadmium, copper, zinc, lead, chromium, nickel, and arsenic cause hazardous effects on animals, human health, and the environment. This review focuses on mutagenic, carcinogenic, and teratogenic effects of HM , mechanism, organ toxicity, available remedies in the market, and their side effects. Also, emphasis is given to alternative systems of medicine to treat HM toxicity.
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spelling pubmed-95562532022-10-13 Mutagenic, Carcinogenic, and Teratogenic Effect of Heavy Metals Dasharathy, Sukeerthi Arjunan, Selvam Maliyur Basavaraju, Anusha Murugasen, Vidya Ramachandran, Saravanan Keshav, Rohini Murugan, Rajadurai Evid Based Complement Alternat Med Review Article Heavy metal (HM)-induced toxicity and its associated complications have become a major issue in the medical world. HMs are not biodegradable, enter into the food chain, and gets accumulated in the living systems. Increased concentrations and accumulation of HMs can cause severely damaging effects and severe complications in living organisms and can even lead to the death of the organism. In Ayurvedic medicine, ingredients of natural origin, including whole plants or certain portions of the plant, animal sources, and minerals, are used for therapeutic purposes as medicine, both alone and in combination. HM such as cadmium, copper, zinc, lead, chromium, nickel, and arsenic cause hazardous effects on animals, human health, and the environment. This review focuses on mutagenic, carcinogenic, and teratogenic effects of HM , mechanism, organ toxicity, available remedies in the market, and their side effects. Also, emphasis is given to alternative systems of medicine to treat HM toxicity. Hindawi 2022-10-05 /pmc/articles/PMC9556253/ /pubmed/36248437 http://dx.doi.org/10.1155/2022/8011953 Text en Copyright © 2022 Sukeerthi Dasharathy et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Dasharathy, Sukeerthi
Arjunan, Selvam
Maliyur Basavaraju, Anusha
Murugasen, Vidya
Ramachandran, Saravanan
Keshav, Rohini
Murugan, Rajadurai
Mutagenic, Carcinogenic, and Teratogenic Effect of Heavy Metals
title Mutagenic, Carcinogenic, and Teratogenic Effect of Heavy Metals
title_full Mutagenic, Carcinogenic, and Teratogenic Effect of Heavy Metals
title_fullStr Mutagenic, Carcinogenic, and Teratogenic Effect of Heavy Metals
title_full_unstemmed Mutagenic, Carcinogenic, and Teratogenic Effect of Heavy Metals
title_short Mutagenic, Carcinogenic, and Teratogenic Effect of Heavy Metals
title_sort mutagenic, carcinogenic, and teratogenic effect of heavy metals
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556253/
https://www.ncbi.nlm.nih.gov/pubmed/36248437
http://dx.doi.org/10.1155/2022/8011953
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