Maturation and circuit integration of transplanted human cortical organoids

Self-organizing neural organoids represent a promising in vitro platform with which to model human development and disease(1–5). However, organoids lack the connectivity that exists in vivo, which limits maturation and makes integration with other circuits that control behaviour impossible. Here we...

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Detalles Bibliográficos
Autores principales: Revah, Omer, Gore, Felicity, Kelley, Kevin W., Andersen, Jimena, Sakai, Noriaki, Chen, Xiaoyu, Li, Min-Yin, Birey, Fikri, Yang, Xiao, Saw, Nay L., Baker, Samuel W., Amin, Neal D., Kulkarni, Shravanti, Mudipalli, Rachana, Cui, Bianxiao, Nishino, Seiji, Grant, Gerald A., Knowles, Juliet K., Shamloo, Mehrdad, Huguenard, John R., Deisseroth, Karl, Pașca, Sergiu P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556304/
https://www.ncbi.nlm.nih.gov/pubmed/36224417
http://dx.doi.org/10.1038/s41586-022-05277-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556304/
https://www.ncbi.nlm.nih.gov/pubmed/36224417
http://dx.doi.org/10.1038/s41586-022-05277-w

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