Heart Rate Variability in Children and Adolescents with Autism, ADHD and Co-occurring Autism and ADHD, During Passive and Active Experimental Conditions

Despite overlaps in clinical symptomatology, autism and ADHD may be associated with opposite autonomic arousal profiles which might partly explain altered cognitive and global functioning. We investigated autonomic arousal in 106 children/adolescents with autism, ADHD, co-occurring autism/ADHD, and...

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Autores principales: Bellato, Alessio, Arora, Iti, Kochhar, Puja, Ropar, Danielle, Hollis, Chris, Groom, Madeleine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556357/
https://www.ncbi.nlm.nih.gov/pubmed/34716841
http://dx.doi.org/10.1007/s10803-021-05244-w
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author Bellato, Alessio
Arora, Iti
Kochhar, Puja
Ropar, Danielle
Hollis, Chris
Groom, Madeleine J.
author_facet Bellato, Alessio
Arora, Iti
Kochhar, Puja
Ropar, Danielle
Hollis, Chris
Groom, Madeleine J.
author_sort Bellato, Alessio
collection PubMed
description Despite overlaps in clinical symptomatology, autism and ADHD may be associated with opposite autonomic arousal profiles which might partly explain altered cognitive and global functioning. We investigated autonomic arousal in 106 children/adolescents with autism, ADHD, co-occurring autism/ADHD, and neurotypical controls. Heart rate variability was recorded during resting-state, a ‘passive’ auditory oddball task and an ‘active’ response conflict task. Autistic children showed hyper-arousal during the active task, while those with ADHD showed hypo-arousal during resting-state and the passive task. Irrespective of diagnosis, children characterised by hyper-arousal showed more severe autistic symptomatology, increased anxiety and reduced global functioning than those displaying hypo-arousal, suggesting the importance of considering individual autonomic arousal profiles for differential diagnosis of autism/ADHD and when developing personalised interventions. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10803-021-05244-w.
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spelling pubmed-95563572022-10-14 Heart Rate Variability in Children and Adolescents with Autism, ADHD and Co-occurring Autism and ADHD, During Passive and Active Experimental Conditions Bellato, Alessio Arora, Iti Kochhar, Puja Ropar, Danielle Hollis, Chris Groom, Madeleine J. J Autism Dev Disord Original Paper Despite overlaps in clinical symptomatology, autism and ADHD may be associated with opposite autonomic arousal profiles which might partly explain altered cognitive and global functioning. We investigated autonomic arousal in 106 children/adolescents with autism, ADHD, co-occurring autism/ADHD, and neurotypical controls. Heart rate variability was recorded during resting-state, a ‘passive’ auditory oddball task and an ‘active’ response conflict task. Autistic children showed hyper-arousal during the active task, while those with ADHD showed hypo-arousal during resting-state and the passive task. Irrespective of diagnosis, children characterised by hyper-arousal showed more severe autistic symptomatology, increased anxiety and reduced global functioning than those displaying hypo-arousal, suggesting the importance of considering individual autonomic arousal profiles for differential diagnosis of autism/ADHD and when developing personalised interventions. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10803-021-05244-w. Springer US 2021-10-30 2022 /pmc/articles/PMC9556357/ /pubmed/34716841 http://dx.doi.org/10.1007/s10803-021-05244-w Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Paper
Bellato, Alessio
Arora, Iti
Kochhar, Puja
Ropar, Danielle
Hollis, Chris
Groom, Madeleine J.
Heart Rate Variability in Children and Adolescents with Autism, ADHD and Co-occurring Autism and ADHD, During Passive and Active Experimental Conditions
title Heart Rate Variability in Children and Adolescents with Autism, ADHD and Co-occurring Autism and ADHD, During Passive and Active Experimental Conditions
title_full Heart Rate Variability in Children and Adolescents with Autism, ADHD and Co-occurring Autism and ADHD, During Passive and Active Experimental Conditions
title_fullStr Heart Rate Variability in Children and Adolescents with Autism, ADHD and Co-occurring Autism and ADHD, During Passive and Active Experimental Conditions
title_full_unstemmed Heart Rate Variability in Children and Adolescents with Autism, ADHD and Co-occurring Autism and ADHD, During Passive and Active Experimental Conditions
title_short Heart Rate Variability in Children and Adolescents with Autism, ADHD and Co-occurring Autism and ADHD, During Passive and Active Experimental Conditions
title_sort heart rate variability in children and adolescents with autism, adhd and co-occurring autism and adhd, during passive and active experimental conditions
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556357/
https://www.ncbi.nlm.nih.gov/pubmed/34716841
http://dx.doi.org/10.1007/s10803-021-05244-w
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