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Nasal Irrigation Delivery in Three Post-FESS Models From a Squeeze-bottle Using CFD
PURPOSE: Nasal saline irrigation is highly recommended in patients following functional endoscopic sinus surgery (FESS) to aid the postoperative recovery. Post-FESS patients have significantly altered anatomy leading to markedly different flow dynamics from those found in pre-op or non-diseased airw...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556402/ https://www.ncbi.nlm.nih.gov/pubmed/36056272 http://dx.doi.org/10.1007/s11095-022-03375-y |
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author | Salati, Hana Singh, Narinder Khamooshi, Mehrdad Vahaji, Sara Fletcher, David F. Inthavong, Kiao |
author_facet | Salati, Hana Singh, Narinder Khamooshi, Mehrdad Vahaji, Sara Fletcher, David F. Inthavong, Kiao |
author_sort | Salati, Hana |
collection | PubMed |
description | PURPOSE: Nasal saline irrigation is highly recommended in patients following functional endoscopic sinus surgery (FESS) to aid the postoperative recovery. Post-FESS patients have significantly altered anatomy leading to markedly different flow dynamics from those found in pre-op or non-diseased airways, resulting in unknown flow dynamics. METHODS: This work investigated how the liquid stream disperses through altered nasal cavities following surgery using Computational Fluid Dynamics (CFD). A realistic squeeze profile was determined from physical experiments with a 27-year-old male using a squeeze bottle with load sensors. The administration technique involved a head tilt of 45-degrees forward to represent a head position over a sink. After the irrigation event that lasted 4.5 s, the simulation continued for an additional 1.5 s, with the head orientation returning to an upright position. RESULTS: The results demonstrated that a large maxillary sinus ostium on the right side allows saline penetration into this sinus. The increased volume of saline entering the maxillary sinus limits the saline volume available to the rest of the sinonasal cavity and reduces the surface coverage of the other paranasal sinuses. The average wall shear stress was higher on the right side than on the other side for two patients. The results also revealed that head position alters the sinuses’ saline residual, especially the frontal sinuses. CONCLUSION: While greater access to sinuses is achieved through FESS surgery, patients without a nasal septum limits posterior sinus penetration due to the liquid crossing over to the contralateral cavity and exiting the nasal cavity early. |
format | Online Article Text |
id | pubmed-9556402 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-95564022022-10-14 Nasal Irrigation Delivery in Three Post-FESS Models From a Squeeze-bottle Using CFD Salati, Hana Singh, Narinder Khamooshi, Mehrdad Vahaji, Sara Fletcher, David F. Inthavong, Kiao Pharm Res Original Research Article PURPOSE: Nasal saline irrigation is highly recommended in patients following functional endoscopic sinus surgery (FESS) to aid the postoperative recovery. Post-FESS patients have significantly altered anatomy leading to markedly different flow dynamics from those found in pre-op or non-diseased airways, resulting in unknown flow dynamics. METHODS: This work investigated how the liquid stream disperses through altered nasal cavities following surgery using Computational Fluid Dynamics (CFD). A realistic squeeze profile was determined from physical experiments with a 27-year-old male using a squeeze bottle with load sensors. The administration technique involved a head tilt of 45-degrees forward to represent a head position over a sink. After the irrigation event that lasted 4.5 s, the simulation continued for an additional 1.5 s, with the head orientation returning to an upright position. RESULTS: The results demonstrated that a large maxillary sinus ostium on the right side allows saline penetration into this sinus. The increased volume of saline entering the maxillary sinus limits the saline volume available to the rest of the sinonasal cavity and reduces the surface coverage of the other paranasal sinuses. The average wall shear stress was higher on the right side than on the other side for two patients. The results also revealed that head position alters the sinuses’ saline residual, especially the frontal sinuses. CONCLUSION: While greater access to sinuses is achieved through FESS surgery, patients without a nasal septum limits posterior sinus penetration due to the liquid crossing over to the contralateral cavity and exiting the nasal cavity early. Springer US 2022-09-02 2022 /pmc/articles/PMC9556402/ /pubmed/36056272 http://dx.doi.org/10.1007/s11095-022-03375-y Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Research Article Salati, Hana Singh, Narinder Khamooshi, Mehrdad Vahaji, Sara Fletcher, David F. Inthavong, Kiao Nasal Irrigation Delivery in Three Post-FESS Models From a Squeeze-bottle Using CFD |
title | Nasal Irrigation Delivery in Three Post-FESS Models From a Squeeze-bottle Using CFD |
title_full | Nasal Irrigation Delivery in Three Post-FESS Models From a Squeeze-bottle Using CFD |
title_fullStr | Nasal Irrigation Delivery in Three Post-FESS Models From a Squeeze-bottle Using CFD |
title_full_unstemmed | Nasal Irrigation Delivery in Three Post-FESS Models From a Squeeze-bottle Using CFD |
title_short | Nasal Irrigation Delivery in Three Post-FESS Models From a Squeeze-bottle Using CFD |
title_sort | nasal irrigation delivery in three post-fess models from a squeeze-bottle using cfd |
topic | Original Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556402/ https://www.ncbi.nlm.nih.gov/pubmed/36056272 http://dx.doi.org/10.1007/s11095-022-03375-y |
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