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Nasal Irrigation Delivery in Three Post-FESS Models From a Squeeze-bottle Using CFD

PURPOSE: Nasal saline irrigation is highly recommended in patients following functional endoscopic sinus surgery (FESS) to aid the postoperative recovery. Post-FESS patients have significantly altered anatomy leading to markedly different flow dynamics from those found in pre-op or non-diseased airw...

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Autores principales: Salati, Hana, Singh, Narinder, Khamooshi, Mehrdad, Vahaji, Sara, Fletcher, David F., Inthavong, Kiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556402/
https://www.ncbi.nlm.nih.gov/pubmed/36056272
http://dx.doi.org/10.1007/s11095-022-03375-y
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author Salati, Hana
Singh, Narinder
Khamooshi, Mehrdad
Vahaji, Sara
Fletcher, David F.
Inthavong, Kiao
author_facet Salati, Hana
Singh, Narinder
Khamooshi, Mehrdad
Vahaji, Sara
Fletcher, David F.
Inthavong, Kiao
author_sort Salati, Hana
collection PubMed
description PURPOSE: Nasal saline irrigation is highly recommended in patients following functional endoscopic sinus surgery (FESS) to aid the postoperative recovery. Post-FESS patients have significantly altered anatomy leading to markedly different flow dynamics from those found in pre-op or non-diseased airways, resulting in unknown flow dynamics. METHODS: This work investigated how the liquid stream disperses through altered nasal cavities following surgery using Computational Fluid Dynamics (CFD). A realistic squeeze profile was determined from physical experiments with a 27-year-old male using a squeeze bottle with load sensors. The administration technique involved a head tilt of 45-degrees forward to represent a head position over a sink. After the irrigation event that lasted 4.5 s, the simulation continued for an additional 1.5 s, with the head orientation returning to an upright position. RESULTS: The results demonstrated that a large maxillary sinus ostium on the right side allows saline penetration into this sinus. The increased volume of saline entering the maxillary sinus limits the saline volume available to the rest of the sinonasal cavity and reduces the surface coverage of the other paranasal sinuses. The average wall shear stress was higher on the right side than on the other side for two patients. The results also revealed that head position alters the sinuses’ saline residual, especially the frontal sinuses. CONCLUSION: While greater access to sinuses is achieved through FESS surgery, patients without a nasal septum limits posterior sinus penetration due to the liquid crossing over to the contralateral cavity and exiting the nasal cavity early.
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spelling pubmed-95564022022-10-14 Nasal Irrigation Delivery in Three Post-FESS Models From a Squeeze-bottle Using CFD Salati, Hana Singh, Narinder Khamooshi, Mehrdad Vahaji, Sara Fletcher, David F. Inthavong, Kiao Pharm Res Original Research Article PURPOSE: Nasal saline irrigation is highly recommended in patients following functional endoscopic sinus surgery (FESS) to aid the postoperative recovery. Post-FESS patients have significantly altered anatomy leading to markedly different flow dynamics from those found in pre-op or non-diseased airways, resulting in unknown flow dynamics. METHODS: This work investigated how the liquid stream disperses through altered nasal cavities following surgery using Computational Fluid Dynamics (CFD). A realistic squeeze profile was determined from physical experiments with a 27-year-old male using a squeeze bottle with load sensors. The administration technique involved a head tilt of 45-degrees forward to represent a head position over a sink. After the irrigation event that lasted 4.5 s, the simulation continued for an additional 1.5 s, with the head orientation returning to an upright position. RESULTS: The results demonstrated that a large maxillary sinus ostium on the right side allows saline penetration into this sinus. The increased volume of saline entering the maxillary sinus limits the saline volume available to the rest of the sinonasal cavity and reduces the surface coverage of the other paranasal sinuses. The average wall shear stress was higher on the right side than on the other side for two patients. The results also revealed that head position alters the sinuses’ saline residual, especially the frontal sinuses. CONCLUSION: While greater access to sinuses is achieved through FESS surgery, patients without a nasal septum limits posterior sinus penetration due to the liquid crossing over to the contralateral cavity and exiting the nasal cavity early. Springer US 2022-09-02 2022 /pmc/articles/PMC9556402/ /pubmed/36056272 http://dx.doi.org/10.1007/s11095-022-03375-y Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Research Article
Salati, Hana
Singh, Narinder
Khamooshi, Mehrdad
Vahaji, Sara
Fletcher, David F.
Inthavong, Kiao
Nasal Irrigation Delivery in Three Post-FESS Models From a Squeeze-bottle Using CFD
title Nasal Irrigation Delivery in Three Post-FESS Models From a Squeeze-bottle Using CFD
title_full Nasal Irrigation Delivery in Three Post-FESS Models From a Squeeze-bottle Using CFD
title_fullStr Nasal Irrigation Delivery in Three Post-FESS Models From a Squeeze-bottle Using CFD
title_full_unstemmed Nasal Irrigation Delivery in Three Post-FESS Models From a Squeeze-bottle Using CFD
title_short Nasal Irrigation Delivery in Three Post-FESS Models From a Squeeze-bottle Using CFD
title_sort nasal irrigation delivery in three post-fess models from a squeeze-bottle using cfd
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556402/
https://www.ncbi.nlm.nih.gov/pubmed/36056272
http://dx.doi.org/10.1007/s11095-022-03375-y
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