Metformin alleviates neurocognitive impairment in aging via activation of AMPK/BDNF/PI3K pathway

Slowing down age-related neurocognitive impairment has been a challenge. We evaluated the therapeutic effects of metformin in d-galactose-induced aging. Additionally, we studied the potential molecular mechanisms that could be responsible for metformin's anti-aging effects. Thirty male rats wer...

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Detalles Bibliográficos
Autores principales: Ameen, Omnia, Samaka, Rehab M., Abo-Elsoud, Reda A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556637/
https://www.ncbi.nlm.nih.gov/pubmed/36224264
http://dx.doi.org/10.1038/s41598-022-20945-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556637/
https://www.ncbi.nlm.nih.gov/pubmed/36224264
http://dx.doi.org/10.1038/s41598-022-20945-7

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