Novel peanut-specific human IgE monoclonal antibodies enable screens for inhibitors of the effector phase in food allergy

BACKGROUND: 10% of US residents have food allergies, including 2% with peanut allergy. Mast cell mediators released during the allergy effector phase drive allergic reactions. Therefore, targeting sensitized mast cells may prevent food allergy symptoms. OBJECTIVE: We used novel, human, allergen-spec...

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Detalles Bibliográficos
Autores principales: Suber, Jada, Zhang, Yugen, Ye, Ping, Guo, Rishu, Burks, A. Wesley, Kulis, Michael D., Smith, Scott A., Iweala, Onyinye I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556733/
https://www.ncbi.nlm.nih.gov/pubmed/36248809
http://dx.doi.org/10.3389/fimmu.2022.974374

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