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Pausing methotrexate prevents impairment of Omicron BA.1 and BA.2 neutralisation after COVID-19 booster vaccination

OBJECTIVE: The level of neutralising capacity against Omicron BA.1 and BA.2 after third COVID-19 vaccination in patients on paused or continuous methotrexate (MTX) therapy is unclear. METHODS: In this observational cohort study, neutralising serum activity against SARS-CoV-2 wild-type (Wu01) and var...

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Detalles Bibliográficos
Autores principales: Habermann, Elisa, Gieselmann, Lutz, Tober-Lau, Pinkus, Klotsche, Jens, Albach, Fredrik Nils, ten Hagen, Alexander, Zernicke, Jan, Ahmadov, Elvin, Arumahandi de Silva, Amanthi Nadira, Frommert, Leonie Maria, Kurth, Florian, Sander, Leif Erik, Burmester, Gerd R, Klein, Florian, Biesen, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556747/
https://www.ncbi.nlm.nih.gov/pubmed/36216410
http://dx.doi.org/10.1136/rmdopen-2022-002639