Cargando…

Early stage β-amyloid-membrane interactions modulate lipid dynamics and influence structural interfaces and fibrillation

Molecular interactions between β-amyloid (Aβ) peptide and membranes contribute to the neuronal toxicity of Aβ and the pathology of Alzheimer’s disease. Neuronal plasma membranes serve as biologically relevant environments for the Aβ aggregation process as well as affect the structural polymorphisms...

Descripción completa

Detalles Bibliográficos
Autores principales: Kenyaga, June M., Cheng, Qinghui, Qiang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556791/
https://www.ncbi.nlm.nih.gov/pubmed/36115457
http://dx.doi.org/10.1016/j.jbc.2022.102491