Cargando…

Rational drug repositioning for coronavirus-associated diseases using directional mapping and side-effect inference

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen of coronavirus disease 2019 (COVID-19), has infected hundreds of millions of people and caused millions of deaths. Looking for valid druggable targets with minimal side effects for the treatment of COVID-19 remains critical....

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jianhua, Liu, Jiaojiao, Luo, Menghan, Cui, Hui, Zhang, Wenwen, Zhao, Ke, Dai, Hongji, Song, Fangfang, Chen, Kexin, Yu, Ying, Zhou, Dongming, Li, Mulin Jun, Yang, Hongxi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556799/ https://www.ncbi.nlm.nih.gov/pubmed/36267550 http://dx.doi.org/10.1016/j.isci.2022.105348

Ejemplares similares

3DCoop: An approach for computational inference of cell-type-specific transcriptional regulators cooperation in 3D chromatin
por: Yi, Xianfu, et al.
Publicado: (2022)

Network-Based Inference Methods for Drug Repositioning
por: Chen, Hailin, et al.
Publicado: (2015)

Pathway-based drug repositioning using causal inference
por: Li, Jiao, et al.
Publicado: (2013)

Repositioning Quinacrine Toward Treatment of Ovarian Cancer by Rational Combination With TRAIL
por: Liang, Rui, et al.
Publicado: (2020)

Recycling side-effects into clinical markers for drug repositioning
por: Duran-Frigola, Miquel, et al.
Publicado: (2012)

Systematic Drug Repositioning Based on Clinical Side-Effects
por: Yang, Lun, et al.
Publicado: (2011)

QTLbase2: an enhanced catalog of human quantitative trait loci on extensive molecular phenotypes
por: Huang, Dandan, et al.
Publicado: (2022)

Rational drug repositioning guided by an integrated pharmacological network of protein, disease and drug
por: Lee, Hee Sook, et al.
Publicado: (2012)

Knowledge Mapping of Drug Repositioning’s Theme and Development
por: Lang, Xiaona, et al.
Publicado: (2023)

Drug repositioning via matrix completion with multi‐view side information
por: Hao, Yunda, et al.
Publicado: (2019)

Drug repositioning is an alternative for the treatment of coronavirus COVID-19
por: Serafin, Marissa B., et al.
Publicado: (2020)

Prediction of Drug-Target Interactions and Drug Repositioning via Network-Based Inference
por: Cheng, Feixiong, et al.
Publicado: (2012)

A review on computer‐aided chemogenomics and drug repositioning for rational COVID‐19 drug discovery
por: Maghsoudi, Saeid, et al.
Publicado: (2022)

A Rational Approach to Drug Repositioning in β-thalassemia: Induction of Fetal Hemoglobin by Established Drugs
por: Prosdocimi, Marco, et al.
Publicado: (2022)

Rational inference strategies and the genesis of polarization and extremism
por: Kvam, Peter D., et al.
Publicado: (2022)

Construction of Drug Network Based on Side Effects and Its Application for Drug Repositioning
por: Ye, Hao, et al.
Publicado: (2014)

Evaluation of connectivity map shows limited reproducibility in drug repositioning
por: Lim, Nathaniel, et al.
Publicado: (2021)

Rational Inference of Beliefs and Desires From Emotional Expressions
por: Wu, Yang, et al.
Publicado: (2017)

Gentamycin Rationally Repositioned to Inhibit miR-34a Ameliorates Oxidative Injury to PC12 Cells
por: Izadi, Zhila, et al.
Publicado: (2022)

Comprehensive network medicine-based drug repositioning via integration of therapeutic efficacy and side effects
por: Paci, Paola, et al.
Publicado: (2022)

Inferring CTCF-binding patterns and anchored loops across human tissues and cell types
por: Xu, Hang, et al.
Publicado: (2023)

A miRNA-Driven Inference Model to Construct Potential Drug-Disease Associations for Drug Repositioning
por: Chen, Hailin, et al.
Publicado: (2015)

Lip repositioning
por: Gaddale, Reetika, et al.
Publicado: (2014)

Mishearing as a Side Effect of Rational Language Comprehension in Noise
por: Van Os, Marjolein, et al.
Publicado: (2021)

The rational use of causal inference to guide reinforcement learning strengthens with age
por: Cohen, Alexandra O., et al.
Publicado: (2020)

A comprehensive review on drug repositioning against coronavirus disease 2019 (COVID19)
por: Rameshrad, Maryam, et al.
Publicado: (2020)

Repositioning of Antiparasitic Drugs for Tumor Treatment
por: Li, Yan-Qi, et al.
Publicado: (2021)

Algorithms for successful repositioning of misplaced left-sided double-lumen tube inserted during lung/thoracic surgery
por: Hariharan, Uma, et al.
Publicado: (2018)

Genome-wide association and functional interrogation identified a variant at 3p26.1 modulating ovarian cancer survival among Chinese women
por: Dai, Hongji, et al.
Publicado: (2021)

DMAP: a connectivity map database to enable identification of novel drug repositioning candidates
por: Huang, Hui, et al.
Publicado: (2015)

Master Regulators Connectivity Map: A Transcription Factors-Centered Approach to Drug Repositioning
por: De Bastiani, Marco A., et al.
Publicado: (2018)

Buccinator muscle repositioning
por: Baghele, Om N.
Publicado: (2012)

Repositioning Drugs for Psychiatry
por: Akhondzadeh, Shahin
Publicado: (2020)

Centromere repositioning and shifts in wheat evolution
por: Zhao, Jing, et al.
Publicado: (2023)

Drug Repositioning Inferred from E2F1-Coregulator Interactions Studies for the Prevention and Treatment of Metastatic Cancers
por: Goody, Deborah, et al.
Publicado: (2019)

Repositioned Drugs for Chagas Disease Unveiled via Structure-Based Drug Repositioning
por: Adasme, Melissa F., et al.
Publicado: (2020)

Drug repositioning in drug discovery of T2DM and repositioning potential of antidiabetic agents
por: Zhu, Sha, et al.
Publicado: (2022)

Error and inference: recent exchanges on experimental reasoning, reliability, and the objectivity and rationality of science
por: Mayo, Deborah G, et al.
Publicado: (2010)

Retrospective Inference as a Form of Bounded Rationality, and Its Beneficial Influence on Learning
por: FitzGerald, Thomas H. B., et al.
Publicado: (2020)

Rational Use of Tocilizumab in the Treatment of Novel Coronavirus Pneumonia
por: Zhang, Shengyu, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_j73lq1f5pg8jho8po0vj44ack4