Deficiency of miRNA-149-3p shaped gut microbiota and enhanced dextran sulfate sodium-induced colitis

Genetic predisposition and disruption of host gut microbiota and immune system can result in inflammatory bowel disease (IBD). Here, we show that miRNA-149-5p (miR-149-5p) and miRNA-149-3p (miR-149-3p) play crucial roles in IBD. Mice lacking miR-149-3p were considerably more susceptible to dextran s...

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Detalles Bibliográficos
Autores principales: Feng, Qingqing, Li, Yuanqiang, Zhang, Hongli, Wang, Ziwei, Nie, Xiaobo, Yao, Denglin, Han, Lu, Chen, Wei-Dong, Wang, Yan-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556934/
https://www.ncbi.nlm.nih.gov/pubmed/36250208
http://dx.doi.org/10.1016/j.omtn.2022.09.018

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