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Case report: Langerhans cell histiocytosis of the temporal bone in children: Challenging diagnosis of a rare disease with some pitfalls
A 4‐year‐old girl was admitted to hospital with disturbance of balance. After being questioned, parents remembered an otitis with effusion 3 months earlier. CT‐scans revealed destruction of both temporal bones. Initial biopsy showed granulomatous, necrotic inflammation, which led to comprehensive di...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556999/ https://www.ncbi.nlm.nih.gov/pubmed/36254150 http://dx.doi.org/10.1002/ccr3.6057 |
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author | Pähler vor der Holte, Anja Welkoborsky´, Hans‐Jürgen |
author_facet | Pähler vor der Holte, Anja Welkoborsky´, Hans‐Jürgen |
author_sort | Pähler vor der Holte, Anja |
collection | PubMed |
description | A 4‐year‐old girl was admitted to hospital with disturbance of balance. After being questioned, parents remembered an otitis with effusion 3 months earlier. CT‐scans revealed destruction of both temporal bones. Initial biopsy showed granulomatous, necrotic inflammation, which led to comprehensive differential diagnoses. A second tissue sample confirmed Langerhans cell histiocytosis. |
format | Online Article Text |
id | pubmed-9556999 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-95569992022-10-16 Case report: Langerhans cell histiocytosis of the temporal bone in children: Challenging diagnosis of a rare disease with some pitfalls Pähler vor der Holte, Anja Welkoborsky´, Hans‐Jürgen Clin Case Rep Case Report A 4‐year‐old girl was admitted to hospital with disturbance of balance. After being questioned, parents remembered an otitis with effusion 3 months earlier. CT‐scans revealed destruction of both temporal bones. Initial biopsy showed granulomatous, necrotic inflammation, which led to comprehensive differential diagnoses. A second tissue sample confirmed Langerhans cell histiocytosis. John Wiley and Sons Inc. 2022-10-12 /pmc/articles/PMC9556999/ /pubmed/36254150 http://dx.doi.org/10.1002/ccr3.6057 Text en © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Case Report Pähler vor der Holte, Anja Welkoborsky´, Hans‐Jürgen Case report: Langerhans cell histiocytosis of the temporal bone in children: Challenging diagnosis of a rare disease with some pitfalls |
title | Case report: Langerhans cell histiocytosis of the temporal bone in children: Challenging diagnosis of a rare disease with some pitfalls |
title_full | Case report: Langerhans cell histiocytosis of the temporal bone in children: Challenging diagnosis of a rare disease with some pitfalls |
title_fullStr | Case report: Langerhans cell histiocytosis of the temporal bone in children: Challenging diagnosis of a rare disease with some pitfalls |
title_full_unstemmed | Case report: Langerhans cell histiocytosis of the temporal bone in children: Challenging diagnosis of a rare disease with some pitfalls |
title_short | Case report: Langerhans cell histiocytosis of the temporal bone in children: Challenging diagnosis of a rare disease with some pitfalls |
title_sort | case report: langerhans cell histiocytosis of the temporal bone in children: challenging diagnosis of a rare disease with some pitfalls |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9556999/ https://www.ncbi.nlm.nih.gov/pubmed/36254150 http://dx.doi.org/10.1002/ccr3.6057 |
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