Cargando…

Early life nociceptive stimulus and fentanyl exposure increase hippocampal neurogenesis and anxiety but do not affect spatial learning and memory

This study aimed to determine whether preemptive fentanyl administration in neonatal rats reduces the impact of a nociceptive stimulus initiated during the first day of life (P1) on hippocampal neurogenesis, behavior, and learning. At P1, Wistar rat pups received either a subcutaneous injection of f...

Descripción completa

Detalles Bibliográficos
Autores principales: Rêgo, Debora da Silva Bandeira, Silva, Clivandir S., Mello, Luiz Eugenio A. M., Leslie, Ana Teresa Figueiredo Stochero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557065/
https://www.ncbi.nlm.nih.gov/pubmed/36248634
http://dx.doi.org/10.3389/fnins.2022.988096