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Early life nociceptive stimulus and fentanyl exposure increase hippocampal neurogenesis and anxiety but do not affect spatial learning and memory
This study aimed to determine whether preemptive fentanyl administration in neonatal rats reduces the impact of a nociceptive stimulus initiated during the first day of life (P1) on hippocampal neurogenesis, behavior, and learning. At P1, Wistar rat pups received either a subcutaneous injection of f...
Autores principales: | Rêgo, Debora da Silva Bandeira, Silva, Clivandir S., Mello, Luiz Eugenio A. M., Leslie, Ana Teresa Figueiredo Stochero |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557065/ https://www.ncbi.nlm.nih.gov/pubmed/36248634 http://dx.doi.org/10.3389/fnins.2022.988096 |
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