Cargando…
Interaction of GC376, a SARS-COV-2 M(PRO) inhibitor, with model lipid membranes
Partitioning and effect of antiviral GC376, a potential SARS-CoV-2 inhibitor, on model lipid membranes was studied using dynamic light scattering (DLS), UV–VIS spectrometry, Excimer fluorescence, Differential scanning calorimetry (DSC) and Small- and Wide-angle X-ray scattering (SAXS/WAXS). Partitio...
Autores principales: | Klacsová, Mária, Čelková, Adriána, Búcsi, Alexander, Martínez, Juan Carlos, Uhríková, Daniela |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557139/ http://dx.doi.org/10.1016/j.colsurfb.2022.112918 |
Ejemplares similares
-
Crystallization of Feline Coronavirus M(pro) With GC376 Reveals Mechanism of Inhibition
por: Lu, Jimmy, et al.
Publicado: (2022) -
Improved SARS-CoV-2 M(pro) inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies
por: Vuong, Wayne, et al.
Publicado: (2021) -
N-Terminal Finger Stabilizes the S1 Pocket for the Reversible Feline Drug GC376 in the SARS-CoV-2 M(pro) Dimer
por: Arutyunova, Elena, et al.
Publicado: (2021) -
Stabilization of the Dimeric State of SARS-CoV-2 Main Protease by GC376 and Nirmatrelvir
por: Paciaroni, Alessandro, et al.
Publicado: (2023) -
Structure basis for inhibition of SARS-CoV-2 by the feline drug GC376
por: Luan, Xiao-dong, et al.
Publicado: (2022)