Utility of intraoperative real-time near-infrared fluorescence surgery for spinal schwannoma

The authors report the first cases of fluorescence-guided spinal surgery of schwannomas using near-infrared fluorescence imaging with the delayed window indocyanine (ICG) green (DWIG) technique for accurate real-time intraoperative tumor visualization. Patients with intradural spinal schwannomas rec...

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Detalles Bibliográficos
Autores principales: Muto, Jun, Mine, Yutaka, Nagai, Sota, Shizu, Naoyuki, Takeda, Hiroki, Ikeda, Daiki, Saito, Akifumi, Joko, Masahiro, Hasegawa, Mitsuhiro, Kaneko, Shinjiro, Inoue, Tatsushi, Lee, John Y. K., Hirose, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association of Neurological Surgeons 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9557329/
https://www.ncbi.nlm.nih.gov/pubmed/36284589
http://dx.doi.org/10.3171/2021.10.FOCVID21158
Descripción
Sumario:The authors report the first cases of fluorescence-guided spinal surgery of schwannomas using near-infrared fluorescence imaging with the delayed window indocyanine (ICG) green (DWIG) technique for accurate real-time intraoperative tumor visualization. Patients with intradural spinal schwannomas received 0.5 mg/kg ICG at the beginning of surgery. After 1 hour, using the DWIG technique, near-infrared spectroscopy (NIRS) detected the spinal schwannomas, showing the exact tumor location and boundaries. DWIG with NIRS microscopy confirmed the exact location of spinal schwannomas before and after opening of the dura mater, thereby facilitating successful tumor dissection from the surrounding tissues, tumor resection, and confirmation of tumor removal. The video can be found here: https://stream.cadmore.media/r10.3171/2021.10.FOCVID21158

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