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Calculation of Heat Capacity Changes in Enzyme Catalysis and Ligand Binding

[Image: see text] It has been suggested that heat capacity changes in enzyme catalysis may be the underlying reason for temperature optima that are not related to unfolding of the enzyme. If this were to be a common phenomenon, it would have major implications for our interpretation of enzyme kineti...

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Detalles Bibliográficos
Autores principales: Åqvist, Johan, van der Ent, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558309/
https://www.ncbi.nlm.nih.gov/pubmed/36094903
http://dx.doi.org/10.1021/acs.jctc.2c00646