Cargando…

Systematic Review and Meta-analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia

The association of androgenetic alopecia with metabolic syndrome has been investigated in several studies, with conflicting results. We conducted a meta-analysis to quantitatively evaluate the risk grade of metabolic syndrome and the metabolic profile in patients with androgenetic alopecia compared...

Descripción completa

Detalles Bibliográficos
Autores principales: QIU, Yueqi, ZHOU, Xingyu, FU, Siqi, LUO, Shuaihantian, LI, Yaping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Publication of Acta Dermato-Venereologica 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558341/
https://www.ncbi.nlm.nih.gov/pubmed/34935992
http://dx.doi.org/10.2340/actadv.v101.1012
_version_ 1784807422994415616
author QIU, Yueqi
ZHOU, Xingyu
FU, Siqi
LUO, Shuaihantian
LI, Yaping
author_facet QIU, Yueqi
ZHOU, Xingyu
FU, Siqi
LUO, Shuaihantian
LI, Yaping
author_sort QIU, Yueqi
collection PubMed
description The association of androgenetic alopecia with metabolic syndrome has been investigated in several studies, with conflicting results. We conducted a meta-analysis to quantitatively evaluate the risk grade of metabolic syndrome and the metabolic profile in patients with androgenetic alopecia compared with controls. In total, 19 articles (2,531 participants) satisfied the inclusion criteria. The pooled odds ratio for the prevalence rate of metabolic syndrome between the group with androgenetic alopecia and controls was 3.46 (95% CI 2.38–5.05; p < 0.001). Female sex, early onset, and African ethnicity were associated with an increased risk of metabolic syndrome. Furthermore, patients with androgenetic alopecia had significantly poorer metabolic profiles, such as body mass index, waist circumference, fasting glucose, blood lipids, and blood pressure. It is important for physicians to screen metabolism-related indicators in patients with androgenetic alopecia. More rigorously designed studies and larger sample sizes are required in future studies.
format Online
Article
Text
id pubmed-9558341
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Society for Publication of Acta Dermato-Venereologica
record_format MEDLINE/PubMed
spelling pubmed-95583412022-10-20 Systematic Review and Meta-analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia QIU, Yueqi ZHOU, Xingyu FU, Siqi LUO, Shuaihantian LI, Yaping Acta Derm Venereol Original Article The association of androgenetic alopecia with metabolic syndrome has been investigated in several studies, with conflicting results. We conducted a meta-analysis to quantitatively evaluate the risk grade of metabolic syndrome and the metabolic profile in patients with androgenetic alopecia compared with controls. In total, 19 articles (2,531 participants) satisfied the inclusion criteria. The pooled odds ratio for the prevalence rate of metabolic syndrome between the group with androgenetic alopecia and controls was 3.46 (95% CI 2.38–5.05; p < 0.001). Female sex, early onset, and African ethnicity were associated with an increased risk of metabolic syndrome. Furthermore, patients with androgenetic alopecia had significantly poorer metabolic profiles, such as body mass index, waist circumference, fasting glucose, blood lipids, and blood pressure. It is important for physicians to screen metabolism-related indicators in patients with androgenetic alopecia. More rigorously designed studies and larger sample sizes are required in future studies. Society for Publication of Acta Dermato-Venereologica 2022-02-08 /pmc/articles/PMC9558341/ /pubmed/34935992 http://dx.doi.org/10.2340/actadv.v101.1012 Text en © 2022 Acta Dermato-Venereologica https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the CC BY-NC license
spellingShingle Original Article
QIU, Yueqi
ZHOU, Xingyu
FU, Siqi
LUO, Shuaihantian
LI, Yaping
Systematic Review and Meta-analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia
title Systematic Review and Meta-analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia
title_full Systematic Review and Meta-analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia
title_fullStr Systematic Review and Meta-analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia
title_full_unstemmed Systematic Review and Meta-analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia
title_short Systematic Review and Meta-analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia
title_sort systematic review and meta-analysis of the association between metabolic syndrome and androgenetic alopecia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558341/
https://www.ncbi.nlm.nih.gov/pubmed/34935992
http://dx.doi.org/10.2340/actadv.v101.1012
work_keys_str_mv AT qiuyueqi systematicreviewandmetaanalysisoftheassociationbetweenmetabolicsyndromeandandrogeneticalopecia
AT zhouxingyu systematicreviewandmetaanalysisoftheassociationbetweenmetabolicsyndromeandandrogeneticalopecia
AT fusiqi systematicreviewandmetaanalysisoftheassociationbetweenmetabolicsyndromeandandrogeneticalopecia
AT luoshuaihantian systematicreviewandmetaanalysisoftheassociationbetweenmetabolicsyndromeandandrogeneticalopecia
AT liyaping systematicreviewandmetaanalysisoftheassociationbetweenmetabolicsyndromeandandrogeneticalopecia