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TBX21 Methylation as a Potential Regulator of Immune Suppression in CMS1 Subtype Colorectal Cancer

SIMPLE SUMMARY: Cytotoxic T lymphocytes (CTL) are critical for response to therapy and survival in CRC. Additionally, CTL are required for response to immune checkpoint inhibitor (ICI) therapy which does not work for most CRC patients. We utilized 7 omics datasets, integrating clinical and genomic d...

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Detalles Bibliográficos
Autores principales: Shen, Yuanyuan, Nussbaum, Yulia I., Manjunath, Yariswamy, Hummel, Justin J., Ciorba, Matthew A., Warren, Wesley C., Kaifi, Jussuf T., Papageorgiou, Christos, Cortese, Rene, Shyu, Chi-Ren, Mitchem, Jonathan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558549/
https://www.ncbi.nlm.nih.gov/pubmed/36230517
http://dx.doi.org/10.3390/cancers14194594