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TBX21 Methylation as a Potential Regulator of Immune Suppression in CMS1 Subtype Colorectal Cancer
SIMPLE SUMMARY: Cytotoxic T lymphocytes (CTL) are critical for response to therapy and survival in CRC. Additionally, CTL are required for response to immune checkpoint inhibitor (ICI) therapy which does not work for most CRC patients. We utilized 7 omics datasets, integrating clinical and genomic d...
Autores principales: | Shen, Yuanyuan, Nussbaum, Yulia I., Manjunath, Yariswamy, Hummel, Justin J., Ciorba, Matthew A., Warren, Wesley C., Kaifi, Jussuf T., Papageorgiou, Christos, Cortese, Rene, Shyu, Chi-Ren, Mitchem, Jonathan B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558549/ https://www.ncbi.nlm.nih.gov/pubmed/36230517 http://dx.doi.org/10.3390/cancers14194594 |
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