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Comparison of Hemodynamic Changes in Patients Undergoing Laparoscopic Cholecystectomy using rocuronium and vecuronium for Intubation and Maintenance under General Anesthesia
CONTEXT: The context of the study is to compare and find better muscle relaxant between rocuronium and vecuronium for intubation and maintenance under general anesthesia in patients undergoing laparoscopic cholecystectomy. AIMS: The aim of the study is to measure intubating condition, hemodynamic ch...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558651/ https://www.ncbi.nlm.nih.gov/pubmed/36249153 http://dx.doi.org/10.4103/aer.aer_70_22 |
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author | Juneja, Nikhita Alam, Md Shahbaz Varshney, Vipin Kumar Gogia, Pratiksha Prasad, Mukesh Kumar Jheetay, Gurdeep Singh |
author_facet | Juneja, Nikhita Alam, Md Shahbaz Varshney, Vipin Kumar Gogia, Pratiksha Prasad, Mukesh Kumar Jheetay, Gurdeep Singh |
author_sort | Juneja, Nikhita |
collection | PubMed |
description | CONTEXT: The context of the study is to compare and find better muscle relaxant between rocuronium and vecuronium for intubation and maintenance under general anesthesia in patients undergoing laparoscopic cholecystectomy. AIMS: The aim of the study is to measure intubating condition, hemodynamic changes during intubation and also during maintenance of general anesthesia and to record complications, if any. SETTINGS AND DESIGN: A prospective clinical study conducted in the Department of Anesthesiology in tertiary care center. MATERIALS AND METHODS: A total of 100 patients of the American Society of Anesthesiologists Classes Grade I and II were planned for laparoscopic cholecystectomy were divided into two groups of 50 each. The subjects in the control and study group were put under anesthesia using injection propofol 2.0 mg.kg(−1) along with injection vecuronium 0.10 mg.kg(−1) and injection propofol 2.0 mg.kg(−1) along with injection rocuronium 0.60 mg.kg(−1), respectively. Hemodynamic monitoring and oxygen saturation (SPO(2)) were recorded at various intervals. STATISTICAL ANALYSIS USED: All the collected data were imported into Microsoft Excel, and the statistical analysis was done by using SPSS 25.0 version. RESULTS: The mean heart rate before and after carboperitoneum at different time intervals and before and after extubation was significantly lower in vecuronium group. The mean systolic blood pressure and mean arterial pressure at 1 and 5 minutes after extubation were significantly more among vecuronium group. CONCLUSIONS: Rocuronium is reasonably cardiostable, produces excellent intubation conditions, has a shorter duration of action, and shows minimal cumulative effect. |
format | Online Article Text |
id | pubmed-9558651 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-95586512022-10-14 Comparison of Hemodynamic Changes in Patients Undergoing Laparoscopic Cholecystectomy using rocuronium and vecuronium for Intubation and Maintenance under General Anesthesia Juneja, Nikhita Alam, Md Shahbaz Varshney, Vipin Kumar Gogia, Pratiksha Prasad, Mukesh Kumar Jheetay, Gurdeep Singh Anesth Essays Res Original Article CONTEXT: The context of the study is to compare and find better muscle relaxant between rocuronium and vecuronium for intubation and maintenance under general anesthesia in patients undergoing laparoscopic cholecystectomy. AIMS: The aim of the study is to measure intubating condition, hemodynamic changes during intubation and also during maintenance of general anesthesia and to record complications, if any. SETTINGS AND DESIGN: A prospective clinical study conducted in the Department of Anesthesiology in tertiary care center. MATERIALS AND METHODS: A total of 100 patients of the American Society of Anesthesiologists Classes Grade I and II were planned for laparoscopic cholecystectomy were divided into two groups of 50 each. The subjects in the control and study group were put under anesthesia using injection propofol 2.0 mg.kg(−1) along with injection vecuronium 0.10 mg.kg(−1) and injection propofol 2.0 mg.kg(−1) along with injection rocuronium 0.60 mg.kg(−1), respectively. Hemodynamic monitoring and oxygen saturation (SPO(2)) were recorded at various intervals. STATISTICAL ANALYSIS USED: All the collected data were imported into Microsoft Excel, and the statistical analysis was done by using SPSS 25.0 version. RESULTS: The mean heart rate before and after carboperitoneum at different time intervals and before and after extubation was significantly lower in vecuronium group. The mean systolic blood pressure and mean arterial pressure at 1 and 5 minutes after extubation were significantly more among vecuronium group. CONCLUSIONS: Rocuronium is reasonably cardiostable, produces excellent intubation conditions, has a shorter duration of action, and shows minimal cumulative effect. Wolters Kluwer - Medknow 2022 2022-07-06 /pmc/articles/PMC9558651/ /pubmed/36249153 http://dx.doi.org/10.4103/aer.aer_70_22 Text en Copyright: © 2022 Anesthesia: Essays and Researches https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Juneja, Nikhita Alam, Md Shahbaz Varshney, Vipin Kumar Gogia, Pratiksha Prasad, Mukesh Kumar Jheetay, Gurdeep Singh Comparison of Hemodynamic Changes in Patients Undergoing Laparoscopic Cholecystectomy using rocuronium and vecuronium for Intubation and Maintenance under General Anesthesia |
title | Comparison of Hemodynamic Changes in Patients Undergoing Laparoscopic Cholecystectomy using rocuronium and vecuronium for Intubation and Maintenance under General Anesthesia |
title_full | Comparison of Hemodynamic Changes in Patients Undergoing Laparoscopic Cholecystectomy using rocuronium and vecuronium for Intubation and Maintenance under General Anesthesia |
title_fullStr | Comparison of Hemodynamic Changes in Patients Undergoing Laparoscopic Cholecystectomy using rocuronium and vecuronium for Intubation and Maintenance under General Anesthesia |
title_full_unstemmed | Comparison of Hemodynamic Changes in Patients Undergoing Laparoscopic Cholecystectomy using rocuronium and vecuronium for Intubation and Maintenance under General Anesthesia |
title_short | Comparison of Hemodynamic Changes in Patients Undergoing Laparoscopic Cholecystectomy using rocuronium and vecuronium for Intubation and Maintenance under General Anesthesia |
title_sort | comparison of hemodynamic changes in patients undergoing laparoscopic cholecystectomy using rocuronium and vecuronium for intubation and maintenance under general anesthesia |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558651/ https://www.ncbi.nlm.nih.gov/pubmed/36249153 http://dx.doi.org/10.4103/aer.aer_70_22 |
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