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Detección de infección por Chlamydia trachomatis en mujeres sexualmente activas en Venezuela

INTRODUCTION: Genital Chlamydia trachomatis infection is one of the most frequent in the world; about 85 million new cases of this pathology are registered each year, which causes severe complications in women and newborns. OBJECTIVE: To determine the clinical-epidemiological characteristics of C. t...

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Detalles Bibliográficos
Autores principales: Joya, Milagros, Heredia, Ricardo, Bastidas, Daniel, Bastidas, Gilberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Nacional de Salud 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558775/
https://www.ncbi.nlm.nih.gov/pubmed/36122291
http://dx.doi.org/10.7705/biomedica.6246
Descripción
Sumario:INTRODUCTION: Genital Chlamydia trachomatis infection is one of the most frequent in the world; about 85 million new cases of this pathology are registered each year, which causes severe complications in women and newborns. OBJECTIVE: To determine the clinical-epidemiological characteristics of C. trachomatis infection in sexually active Venezuelan women. MATERIALS AND METHODS: Descriptive, cross-sectional, and field study based on the clinical history and physical examination, detection of infection with immunoenzymatic assay with anti-LPS polyclonal antibody and confirmation of results with molecular biology test. The sample consisted of 100 sexually active women over 12 years of age from Carabobo state, Venezuela. RESULTS: The women were mostly between 20 and 45 years old, in 25% of them IgG antibodies to C. trachomatis were detected and in 84% of these the infection was confirmed by PCR, in none of the women IgM antibodies to C. trachomatis were found. CONCLUSION: Chronic infection characterizes women between 20 and 45 years of age; the immunoenzymatic test yielded false positives corroborated by PCR.