A randomized controlled trial of everolimus for neurocognitive symptoms in PTEN hamartoma tumor syndrome

PTEN hamartoma tumor syndrome (PHTS) is a complex neurodevelopmental disorder characterized by mechanistic target of rapamycin (mTOR) overactivity. Limited data suggest that mTOR inhibitors may be therapeutic. No placebo-controlled studies have examined mTOR inhibition on cognition and behavior in h...

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Detalles Bibliográficos
Autores principales: Srivastava, Siddharth, Jo, Booil, Zhang, Bo, Frazier, Thomas, Gallagher, Anne Snow, Peck, Fleming, Levin, April R, Mondal, Sangeeta, Li, Zetan, Filip-Dhima, Rajna, Geisel, Gregory, Dies, Kira A, Diplock, Amelia, Eng, Charis, Hanna, Rabi, Sahin, Mustafa, Hardan, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558845/
https://www.ncbi.nlm.nih.gov/pubmed/35594551
http://dx.doi.org/10.1093/hmg/ddac111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558845/
https://www.ncbi.nlm.nih.gov/pubmed/35594551
http://dx.doi.org/10.1093/hmg/ddac111

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