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c-Jun-mediated miR-19b expression induces endothelial barrier dysfunction in an in vitro model of hemorrhagic shock
BACKGROUND: Our previous data demonstrated that miR-19b expression was increased in human lung microvascular endothelial cells in-vitro-, in-vivo and in patients with hemorrhagic shock, leading to a decrease in syndecan-1 mRNA and protein and resulting in loss of endothelial barrier function. Howeve...
Autores principales: | Wu, Feng, Wang, Jian-Ying, Dorman, Brooke, Zeineddin, Ahmad, Kozar, Rosemary Ann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9558999/ https://www.ncbi.nlm.nih.gov/pubmed/36224531 http://dx.doi.org/10.1186/s10020-022-00550-0 |
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