Analysis of gene expression levels and their impact on survival in 31 cancer-types patients identifies novel prognostic markers and suggests unexplored immunotherapy treatment options in a wide range of malignancies

BACKGROUND: Immunotherapy has dramatically improved cancer treatment by inhibiting or activating specific cell receptors, thus unleashing the host anti-tumor response. However, the engagement of the three main immune checkpoints so far identified, CTLA4, PD-1 and PD-L1, is effective in a fraction of...

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Detalles Bibliográficos
Autores principales: Giampietri, Claudia, Scatozza, Francesca, Crecca, Elena, Vigiano Benedetti, Virginia, Natali, Pier Giorgio, Facchiano, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559014/
https://www.ncbi.nlm.nih.gov/pubmed/36224560
http://dx.doi.org/10.1186/s12967-022-03670-7

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