Mycobacterial acyl carrier protein suppresses TFEB activation and upregulates miR-155 to inhibit host defense

Mycobacterial acyl carrier protein (AcpM; Rv2244), a key protein involved in Mycobacterium tuberculosis (Mtb) mycolic acid production, has been shown to suppress host cell death during mycobacterial infection. This study reports that mycobacterial AcpM works as an effector to subvert host defense an...

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Detalles Bibliográficos
Autores principales: Paik, Seungwha, Kim, Kyeong Tae, Kim, In Soo, Kim, Young Jae, Kim, Hyeon Ji, Choi, Seunga, Kim, Hwa-Jung, Jo, Eun-Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559204/
https://www.ncbi.nlm.nih.gov/pubmed/36248815
http://dx.doi.org/10.3389/fimmu.2022.946929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559204/
https://www.ncbi.nlm.nih.gov/pubmed/36248815
http://dx.doi.org/10.3389/fimmu.2022.946929

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