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Mycobacterial acyl carrier protein suppresses TFEB activation and upregulates miR-155 to inhibit host defense
Mycobacterial acyl carrier protein (AcpM; Rv2244), a key protein involved in Mycobacterium tuberculosis (Mtb) mycolic acid production, has been shown to suppress host cell death during mycobacterial infection. This study reports that mycobacterial AcpM works as an effector to subvert host defense an...
Autores principales: | Paik, Seungwha, Kim, Kyeong Tae, Kim, In Soo, Kim, Young Jae, Kim, Hyeon Ji, Choi, Seunga, Kim, Hwa-Jung, Jo, Eun-Kyeong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559204/ https://www.ncbi.nlm.nih.gov/pubmed/36248815 http://dx.doi.org/10.3389/fimmu.2022.946929 |
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