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A Case of Sex Cord-Stromal Tumor Originating in the Retroperitoneal Space

A 54-year-old man was seen in the clinic with the chief complaint of epigastric pain radiating to the left groin region and a predominant postprandial abdominal discomfort. Upon examination, a painless round mass with reduced mobility was felt in the left flank during deep palpation of the abdomen....

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Autores principales: Șchiopu, Victor, Butnari, Valentin, Țurcanu, Vasile, Ghidirim, Nicolae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559248/
https://www.ncbi.nlm.nih.gov/pubmed/36258996
http://dx.doi.org/10.7759/cureus.29063
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author Șchiopu, Victor
Butnari, Valentin
Țurcanu, Vasile
Ghidirim, Nicolae
author_facet Șchiopu, Victor
Butnari, Valentin
Țurcanu, Vasile
Ghidirim, Nicolae
author_sort Șchiopu, Victor
collection PubMed
description A 54-year-old man was seen in the clinic with the chief complaint of epigastric pain radiating to the left groin region and a predominant postprandial abdominal discomfort. Upon examination, a painless round mass with reduced mobility was felt in the left flank during deep palpation of the abdomen. His past medical history was irrelevant. Ultrasound and IV contrast-enhanced CT scan confirmed the presence of a large tumor and an exploratory laparotomy for removal of the tumor was performed. The microscopic examination of the specimen confirmed the primary diagnosis of retroperitoneal tumor (RPT) and identified it as an extragonadal germ cell tumor with a vestigial origin, which is a rare type affecting the kidney and adrenal gland. Primitive RPTs are histologically classified as mesenchymal and neuroectodermal or vestigial. These histological types are rarely found in surgical practice and are challenging to diagnose and treat due to the peculiarities of the site of origin where they develop. RPTs are extremely rare and approximately 80% are malignant and detected lately during the disease's course, commonly discovered in advanced stages of local or systemic evolution. Currently, surgical intervention remains the only effective method of treating these tumors.
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spelling pubmed-95592482022-10-17 A Case of Sex Cord-Stromal Tumor Originating in the Retroperitoneal Space Șchiopu, Victor Butnari, Valentin Țurcanu, Vasile Ghidirim, Nicolae Cureus Urology A 54-year-old man was seen in the clinic with the chief complaint of epigastric pain radiating to the left groin region and a predominant postprandial abdominal discomfort. Upon examination, a painless round mass with reduced mobility was felt in the left flank during deep palpation of the abdomen. His past medical history was irrelevant. Ultrasound and IV contrast-enhanced CT scan confirmed the presence of a large tumor and an exploratory laparotomy for removal of the tumor was performed. The microscopic examination of the specimen confirmed the primary diagnosis of retroperitoneal tumor (RPT) and identified it as an extragonadal germ cell tumor with a vestigial origin, which is a rare type affecting the kidney and adrenal gland. Primitive RPTs are histologically classified as mesenchymal and neuroectodermal or vestigial. These histological types are rarely found in surgical practice and are challenging to diagnose and treat due to the peculiarities of the site of origin where they develop. RPTs are extremely rare and approximately 80% are malignant and detected lately during the disease's course, commonly discovered in advanced stages of local or systemic evolution. Currently, surgical intervention remains the only effective method of treating these tumors. Cureus 2022-09-11 /pmc/articles/PMC9559248/ /pubmed/36258996 http://dx.doi.org/10.7759/cureus.29063 Text en Copyright © 2022, Șchiopu et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Urology
Șchiopu, Victor
Butnari, Valentin
Țurcanu, Vasile
Ghidirim, Nicolae
A Case of Sex Cord-Stromal Tumor Originating in the Retroperitoneal Space
title A Case of Sex Cord-Stromal Tumor Originating in the Retroperitoneal Space
title_full A Case of Sex Cord-Stromal Tumor Originating in the Retroperitoneal Space
title_fullStr A Case of Sex Cord-Stromal Tumor Originating in the Retroperitoneal Space
title_full_unstemmed A Case of Sex Cord-Stromal Tumor Originating in the Retroperitoneal Space
title_short A Case of Sex Cord-Stromal Tumor Originating in the Retroperitoneal Space
title_sort case of sex cord-stromal tumor originating in the retroperitoneal space
topic Urology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559248/
https://www.ncbi.nlm.nih.gov/pubmed/36258996
http://dx.doi.org/10.7759/cureus.29063
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